Oral bacteria can amplify gut inflammation

New research from the University of Michigan has homed in on the possible mechanisms by which periodontitis can exacerbate the gut inflammation seen in patients with inflammatory bowel disease (IBD).

It is becoming increasingly clear the trillions of bacteria living inside our bodies have profound effects on our general health. While a great deal of research has focused directly on the gut microbiome, evidence is emerging demonstrating compelling ways our oral bacteria can influence the rest of our body.

This new research set out to explore the mechanisms by which bacteria in the mouth could possibly influence the severity of gastrointestinal disease. In a collaborative effort bringing together gastroenterology and dental research teams, a detailed animal study has presented a convincing mechanistic hypothesis to explain the oft-cited association.

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